Perinatal Omega-3 Deficiency May Condition Future Sensitivity to Food Reward and Impaired Energy Expenditure
This article at a glance
- Is it possible that the quality of food during gestation and around birth sets the stage for the eating behaviour of the offspring when they become adults?
- This study reports that in mice a perinatal deficiency in dietary omega-3 fatty acids has long-lasting effects into adulthood, enhancing the brain circuits for reward, enhancing the anxiety state and reducing spontaneous activity.
- The results provide experimental support for the hypothesis that dietary omega-3 LCPUFA deficiency during pregnancy increases the motivation to eat easily palatable foods that may promote negative emotions, which can further promote overeating and obesity.