Research Summary Archives

Mental Health and Cognition

  • Is DHA Transport Altered in Alzheimer's Disease?

    Several reports have documented the relationship between low intakes of fish or long-chain omega-3 PUFAs (n-3 LC-PUFAs) and an increased risk of developing Alzheimer’s disease or cognitive decline. Some areas of the brain, such as the orbitofrontal cortex, may gradually lose DHA with age. In one stu...

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  • Learning and Behavior in Adolescents Whose Mothers Ate Fish During Pregnancy

    Persistent worries about the potential dangers from consuming fish and the methylmercury they contain continue to frighten women away from eating fish during pregnancy, especially in the U.S. Mercury is present in nearly all seafood in the form of methylmercury. Seafood consumption is already very l...

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  • Depressive Symptoms in Early Pregnancy Linked to Lower Breast Milk DHA Levels

    Some women develop depressive symptoms during or after childbirth, but it is unclear why some women do and others do not. A history of depressive illness and difficult socioeconomic conditions increase the risk of developing this condition, but other factors, including nutrition may contribute as we...

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  • Postpartum Depressive Symptoms Linked to High Omega-6 and Low Omega-3 Intakes

    Depressive illness during and after pregnancy affects from 10% to 40% of women worldwide, according to the World Health Organization. The occurrence of this burdensome condition is higher in less developed countries where treatment may be limited and difficult living conditions complicate the situat...

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  • Challenge: Assessing Brain Fatty Acid Changes During Cognitive Decline

    There is a growing literature about the links between the consumption of fish and shellfish, tissue levels of long-chain omega-3 fatty acids (omega-3s) found in seafood and the odds of developing age-related dementia. The most well known example of advanced mental loss is Alzheimer’s disease, a cond...

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  • Is Suicide in US Military Personnel Related to Low DHA Status?

    Suicide is a global problem, prevalent among adolescents, the elderly and active-duty military personnel. Among US active-duty military, suicide is the second leading cause of death, whereas in the general adult population, it ranks ninth. What attracted popular attention to this high occurrence was...

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  • Long-Chain PUFA Status at Birth May Relate to Behaviors at Age 10

    There is a small, but growing, literature on the relationship between long-chain omega-3 PUFA (n-3 LC-PUFA) status at birth and later child development, cognition and behavior. Do the observations reported in the first year of life extend into later childhood? Do relationships appear later that were...

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  • DHA has Positive Effects in Traumatic Brain Injury

    Traumatic brain injury (Figure) results in about 53,000 deaths in the U.S. every year, with nearly twice that number suffering permanent disability, which sometimes includes diminished cognitive ability. Treatments with long-term benefits are few and of limited effectiveness. One potential treatment...

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  • Is Suicide in US Military Personnel Related to Low DHA Status?

    Suicide is a global problem that is more prevalent among adolescents, the elderly, war veterans and active-duty military personnel. The latter are of particular concern regarding the Iraq and Afghanistan wars, among whom suicide is the second leading cause of death (13.1%) compared with the ninth ra...

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  • Positive Effects of DHA in Experimental Traumatic Brain Injury

    Traumatic brain injury results in 53,000 deaths in the U.S. every year (Figure), with nearly twice that number suffering permanent disability, including diminished cognitive ability. Treatments with long-term benefits are few and of limited effectiveness.  Progesterone may have neurological benefits...

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